Restoring Synapses,

Restoring Health

Investigational Therapeutics That Restore Brain Synapses

Spinogenix is pioneering first-in-class, investigational therapeutics that restore brain synapses to improve the lives of patients worldwide.

A New Approach to the Brain’s Lost Connections

Spinogenix has designed small molecules to help restore the brain connections (synapses) in neurodegenerative, neuropsychiatric and neurodevelopmental conditions including amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, schizophrenia, Fragile X Syndrome (FXS) and many others.

Latest Press Releases

Spinogenix Recognizes Dr. Craig Erickson following $17.25 Million Autism Research Grant to Cincinnati Children’s Hospital

June 15, 2026

Grant Will Support Spinogenix Chief Medical Advisor’s Research into Precision Medicine and EEG   LOS ANGELES, June 15, 2026 – Spinogenix, Inc., a clinical-stage biopharmaceutical company pioneering novel therapeutics that have the potential to restore synapses to improve...

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Spinogenix Receives U.S. FDA Fast Track Designation for Tazbentetol for the Treatment of ALS

May 5, 2026

Designation Enables an Enhanced Development Path for Tazbentetol and Underscores the Unmet Need for New Treatments In ALS Milestone Follows Recent Announcement of Phase 2a Results Showing Preliminary Evidence that...

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Spinogenix to Present Preclinical Results at ARVO 2026 Demonstrating Neuroprotective Effects of Tazbentetol in Glaucoma and Diabetic Retinopathy Models

May 3, 2026

New Preclinical Data Show Tazbentetol Reduces Retinal Cell Loss and Preserves Visual Function in Glaucoma and Diabetic Retinopathy Models LOS ANGELES, May 3, 2026 — Spinogenix, Inc., a clinical-stage biopharmaceutical...

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In the News

Spinogenix’s Alzheimer’s drug touts disease-modifying potential in Phase IIa study

December 9, 2025

Topline data from a completed phase 2a trial (NCT05882695) highlighted the therapeutic benefits of SPG302, a synaptic regenerative drug, to treat patients with amyotrophic lateral sclerosis (ALS). All told, treatment...

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From the Blog

Rethinking Alzheimer’s Treatment: It’s Time for a New Playbook in the Fight for Memory

December 1, 2025

Authored by Stella Sarraf, PhD CEO, Founder In September, we recognized World Alzheimer’s Month and championed the much-needed attention and awareness to one of the greatest health crises of our...

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Featured Videos

Inside A Bold New Approach To Alzheimer’s (Forbes)

Advancing Neurotherapeutics for Fragile X and Beyond with Spinogenix’s Dr. Craig Erickson (Xtalks)